Progestins act mainly on the female reproductive system and have found many therapeutic uses in the Women's Health field. They are employed as a component of oral contraceptives, used in hormone replacement therapy and for a variety of menopausal/post menopausal disorders. They are also used in the management of certain hormone dependent breast and endometrial carcinomas. Megestrol acetate, has found a further use in the treatment of AIDS related cachexia. Pfizer CentreSource offers the following Progestins to the market.